87 y/o female admitted with episodic myoclonus. She had an underlying history of dementia, Alzheimer's type on treatment with memanting and several other medications. Her symptoms were rhythmic movements of the bilateral upper extremities and neck muscles.
Pearls:
Myoclonus can occur as part of the natural progression of Alzheimer's, but if it is early and pronounced other diagnoses such as CJD should be considered.
Certain medications (including memantine) can cause myoclonus when drug levels become high.
Clonazepam is an effective intervention for myoclonic symptoms.
Review of topics covered in morning report, M&m, and core conferences with links to supplemental reading material.
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