MR wrap-up from week of Aug 8

Interesting case of Werneckie's encephalopathy - there is an images in clinical medicine from a few years back that demonstrates the characteristic lesions of this disease, which were noted on the patient discussed in morning report.  Keep in mind the clinical triad of Werneckies - encephalopathy, ataxia, and oculomotor dysfunction.

The cost of intravenous vitamins and folate for prevention of Werneckies is excessive - $100 per "banana bag" vs a few cents for oral vitamin supplementation.  Treatment of established Werneckies is more complicated, and there is some literature that full course intravenous repletion in symptomatic cases may be cost saving in the long run due to concerns of patient compliance with oral thiamine replacement after discharge.

Another case this week was a patient with acute monocular vision loss - in this case suspected to be optic neuritis.  Great NEJM review on the topic here.




Also - for this week's ECG of the week, from a diabetic presenting with subacute dyspnea, shows inferior Q waves consistent with prior MI, which in this case was "silent" and came to clinical attention after the heart failure admission.  Up to 20% of MI's resulting in Q waves on ECG may be silent, and up to 8% of a high risk population can have myocardial scars from previous MIs without clinical or ECG evidence.