Fanconi syndrome: proximal tubular dysfunction with resultant type2 RTA associated with renal loss of glucose, amino acids, magnesium, and potassium. Associated with use of tenofovir, codofovir, and tetracycline. Think of this when urine dipstick is positive for glucose but the serum glucose is <150.
Remember the three most common causes of acute kidney injury in hospitalized patinets: volume depletion, medications, and radiocontrast administration. A nice study covering this subject was published in the American Journal of Kidney Diseases 2002, Vol 39: 930-936. Full text available via MD Consult at:
AJKD Vol 39:930 - 936
Also, remember to use the RIFLE criteria for staging AKI patients. Risk = Cr increased 1.5X, Injury = 2X, and Failure = 3X. L = persistent total loss of kidney function > 4 weeks, and E = ESRD. This has been validated as a prognostic tool in patients who develope AKI. A review of the literature from 2007 is linked below:
Kidney International, 2008 73:538
Review of topics covered in morning report, M&m, and core conferences with links to supplemental reading material.
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